Editing Dr. Mario World

As with previous ''Dr. Mario'' games, the main and most common objective is to eliminate all of the viruses on the screen by connecting capsules of the same color to each of them, although instead of the capsules descending, the game's gravity is directed upwards with the viruses positioned towards the top of the screen. The player first drags a capsule from the bottom of the screen onto the field to use it, and the player can drag it again to move it or increase its "falling" speed, or tap it to rotate it horizontally or vertically; if there is an open space for the capsule to fit through, the player can drag the capsule towards that open space as well. Viruses are eliminated if three (as opposed to four) or more of the same color are matched.<ref name=Overview>Nintendo Mobile (June 17, 2019). [https://youtu.be/8b4DNKfs_tU Welcome to ''Dr. Mario World'']. ''YouTube''. Retrieved June 18, 2019.</ref> If the player uses a half of a capsule to eliminate viruses, the other half remains, and the player can drag it around as an ordinary capsule if it is free to go up the screen. Players earn a rainbow capsule if they make seven matches that eliminate viruses; these rainbow capsules can be used in tandem with pills of any color to eliminate viruses, though they take up only one tile on the screen. The classic red, blue, and yellow viruses return, while new green, purple, light-blue, and pink viruses make their debut,<ref name=Website>[https://drmario-world.com/en-US/index.html Official website]</ref> though purple viruses have never appeared in any stage before.

Depending on the stage, various obstacles may appear on the field, including [[Empty Block]]s and [[Brick Block]]s, and viruses can be hidden inside the Brick Blocks. Helpful objects such as [[shell]]s, [[exploder]]s, and [[skill charger]]s can also appear among the viruses. When matched with capsules of the same color, the helpful objects help out the player: Shells clear out viruses within the same row, exploders eliminate surrounding viruses, and skill chargers significantly fill the doctor's skill meter. There are various objects that act as obstacles, such as [[ice]] that may trap viruses that require a match to remove the ice, [[bubble]]s that shield them from capsules once before they disappear, and cages that require clearing the [[lock block]] to release them.<ref name=Overview/>

Special items can be used prior to entering a stage and while in the middle of a stage, aiding players to clear the stage. Dr. Toad gives out free items for a trial use, but after the single use, players need to purchase the items with diamonds or coins.